Efecto antiulceroso gástrico del extracto etanólico de las hojas secas de Senecio canescens (Humb. & Bonpl.) Cuatrec. “huila huila” en ratas albinas cepa Holtzman
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Universidad Privada de Huancayo Franklin Roosevelt
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Objetivo: Determinar si el extracto etanólico de las hojas secas de Senecio canescens (Humb. & Bonpl.) Cuatrec. “HUILA HUILA” tiene efecto antiulceroso gástrico en ratas albinas Cepa Holtzman. Método: Es experimental, se utilizó Ibuprofeno para la inducción en dosis de 400 mg/Kg por vía oral y se formó 06 grupos: Suero fisiológico 5 mL/Kg; Ibuprofeno 400 mg/Kg; tres grupos con extracto etanólico 100 mg/Kg, 200 mg/Kg, 400 mg/Kg y la Ranitidina 50 mg/Kg. Resultados: La dosis del extracto etanólico de 400 mg/Kg presentó (78%), 200 mg/Kg (46%), 100 mg/Kg (22%) y la ranitidina obtuvo 72% de inhibición de lesión gástrica. Se concluye que el extracto etanólico de “HUILA HUILA”; presentó efecto antiulceroso en ratas albinas inducidas a úlcera gástrica
Objective: To determine if the ethanolic extract of dried leaves of Senecio canescens (Humb. & Bonpl.) Cuatrec. "HUILA HUILA" has gastric antiulcer effect in albino rats Holtzman strain. Method: It is experimental, Ibuprofen was used for induction in doses of 400 mg/kg orally and 06 groups were formed: Physiological saline solution 5 mL/kg; Ibuprofen 400 mg/kg; three groups with ethanolic extract 100 mg/kg, 200 mg/kg, 400 mg/kg and Ranitidine 50 mg/kg. Results: The ethanolic extract dose of 400 mg/kg presented (78%), 200 mg/kg (46%), 100 mg/kg (22%) and ranitidine obtained 72% inhibition of gastric lesion. It is concluded that the ethanolic extract of "HUILA HUILA" presented anti-ulcer effect in albino rats induced to gastric ulcer
Objective: To determine if the ethanolic extract of dried leaves of Senecio canescens (Humb. & Bonpl.) Cuatrec. "HUILA HUILA" has gastric antiulcer effect in albino rats Holtzman strain. Method: It is experimental, Ibuprofen was used for induction in doses of 400 mg/kg orally and 06 groups were formed: Physiological saline solution 5 mL/kg; Ibuprofen 400 mg/kg; three groups with ethanolic extract 100 mg/kg, 200 mg/kg, 400 mg/kg and Ranitidine 50 mg/kg. Results: The ethanolic extract dose of 400 mg/kg presented (78%), 200 mg/kg (46%), 100 mg/kg (22%) and ranitidine obtained 72% inhibition of gastric lesion. It is concluded that the ethanolic extract of "HUILA HUILA" presented anti-ulcer effect in albino rats induced to gastric ulcer
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