Efecto cicatrizante de la crema con extracto etanólico de hojas de Byrsonima crassifolia (Lam.) A.H. Gentry en ratones albinos
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Universidad Privada de Huancayo Franklin Roosevelt
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Las heridas cutáneas representan un problema de salud que motiva la búsqueda de alternativas vegetales. El estudio evaluó el efecto cicatrizante de una crema con extracto etanólico de hojas de Byrsonima crassifolia “indano”. Se realizó una investigación cuantitativa, aplicada, experimental y aleatorizada en 24 ratones albinos. El análisis fitoquímico identificó saponinas, alcaloides, compuestos fenólicos, flavonoides y taninos. Se elaboraron cremas con extracto al 1 %, 3 % y 5 %, comparadas con el control ´positivo. La fuerza de tensión fue de 35.5 g (1 %), 55.8 g (3 %) y 60.3 g (5 %). El efecto cicatrizante aumentó conforme se incrementó la concentración del extracto. Se concluyó que la crema presentó efecto cicatrizante, aunque inferior al control positivo.
Skin wounds represent a health issue that drives the search for plant-based alternatives. This study evaluated the wound-healing effect of a cream containing an ethanolic extract of *Byrsonima crassifolia* ("indano") leaves. A quantitative, applied, experimental, and randomized study was conducted using 24 albino mice. Phytochemical analysis identified saponins, alkaloids, phenolic compounds, flavonoids, and tannins. Creams were formulated with extract concentrations of 1%, 3%, and 5% and compared against a positive control. Tensile strength values were 35.5 g (1%), 55.8 g (3%), and 60.3 g (5%). The wound-healing effect increased alongside the extract concentration. It was concluded that the cream exhibited a wound-healing effect, although it was inferior to that of the positive control.
Skin wounds represent a health issue that drives the search for plant-based alternatives. This study evaluated the wound-healing effect of a cream containing an ethanolic extract of *Byrsonima crassifolia* ("indano") leaves. A quantitative, applied, experimental, and randomized study was conducted using 24 albino mice. Phytochemical analysis identified saponins, alkaloids, phenolic compounds, flavonoids, and tannins. Creams were formulated with extract concentrations of 1%, 3%, and 5% and compared against a positive control. Tensile strength values were 35.5 g (1%), 55.8 g (3%), and 60.3 g (5%). The wound-healing effect increased alongside the extract concentration. It was concluded that the cream exhibited a wound-healing effect, although it was inferior to that of the positive control.
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