Efecto antimicótico in vitro del extracto hidroalcohólico de las hojas secas de Aloysia citrodora Paláu (cedrón) frente a Candida albicans
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Universidad Privada de Huancayo Franklin Roosevelt
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La investigación tuvo como objetivo determinar el efecto antimicótico in vitro del extracto hidroalcohólico de hojas secas de Aloysia citrodora Paláu frente a Candida albicans. Fue de enfoque cuantitativo, tipo experimental y nivel explicativo, utilizando cultivos de Candida albicans y concentraciones del extracto al 5 %, 10 % y 20 %, con nistatina como control positivo. Los resultados mostraron halos de inhibición de 9,10 mm, 15,07 mm y 17,10 mm, respectivamente, frente a 18,50 mm de la nistatina, con diferencias significativas (p < 0,05). Se concluyó que el extracto presentó actividad antimicótica, destacando la concentración al 20 % como la de mayor efecto inhibitorio.
The research aimed to determine the in vitro antifungal effect of a hydroalcoholic extract of dried *Aloysia citrodora* Paláu leaves against *Candida albicans*. The study employed a quantitative approach, an experimental design, and an explanatory level, using *Candida albicans* cultures and extract concentrations of 5%, 10%, and 20%, with nystatin as a positive control. The results showed zones of inhibition of 9.10 mm, 15.07 mm, and 17.10 mm, respectively, compared to 18.50 mm for nystatin, with significant differences (p < 0.05). It was concluded that the extract exhibited antifungal activity, with the 20% concentration showing the greatest inhibitory effect.
The research aimed to determine the in vitro antifungal effect of a hydroalcoholic extract of dried *Aloysia citrodora* Paláu leaves against *Candida albicans*. The study employed a quantitative approach, an experimental design, and an explanatory level, using *Candida albicans* cultures and extract concentrations of 5%, 10%, and 20%, with nystatin as a positive control. The results showed zones of inhibition of 9.10 mm, 15.07 mm, and 17.10 mm, respectively, compared to 18.50 mm for nystatin, with significant differences (p < 0.05). It was concluded that the extract exhibited antifungal activity, with the 20% concentration showing the greatest inhibitory effect.
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