Evaluación del efecto antimicótico in vitro del extracto hidroalcohólico de hojas de Verbena officinalis L. (verbena) frente a Trichophyton sp.
| dc.contributor.advisor | Jesus Carbajal, Orlando | |
| dc.contributor.author | Navarro Tuesta, Isabel del Rocio | |
| dc.contributor.author | Samanez Samata, Rosmery | |
| dc.date.accessioned | 2026-08-19T16:08:32Z | |
| dc.date.issued | 2026-08-11 | |
| dc.description.abstract | La investigación tuvo como objetivo determinar el efecto antimicótico in vitro del extracto hidroalcohólico de hojas de Verbena officinalis L. frente a Trichophyton sp. Se desarrolló bajo un enfoque cuantitativo, de tipo experimental y nivel explicativo. La muestra estuvo constituida por el extracto hidroalcohólico de hojas de Verbena officinalis L. a concentraciones de 50 %, 75 % y 100 %, evaluado mediante difusión en agar por pozos, utilizando fluconazol como control positivo. El tamizaje fitoquímico evidenció alcaloides, flavonoides, resinas y aminoácidos libres en alta intensidad (+++), además de otros metabolitos secundarios. El análisis mediante ANOVA y Tukey evidenció diferencias significativas (p < 0,05). Se concluye que el extracto presentó actividad antimicótica in vitro frente a Trichophyton sp., siendo el 100 % la concentración más efectiva, aunque inferior al fluconazol. | |
| dc.description.abstract | The objective of this research was to determine the in vitro antifungal effect of the hydroalcoholic extract of Verbena officinalis L. leaves against Trichophyton sp. A quantitative, experimental, and explanatory approach was used. The sample consisted of the hydroalcoholic extract of Verbena officinalis L. leaves at concentrations of 50%, 75%, and 100%, evaluated by well diffusion on agar, using fluconazole as a positive control. Phytochemical screening revealed high concentrations (+++) of alkaloids, flavonoids, resins, and free amino acids, as well as other secondary metabolites. Analysis using ANOVA and Tukey's test showed significant differences (p < 0.05). It was concluded that the extract exhibited in vitro antifungal activity against Trichophyton sp., with the 100% concentration being the most effective, although less effective than fluconazole. | |
| dc.format | application/pdf | |
| dc.identifier.citation | Vancouver | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14140/2921 | |
| dc.language.iso | spa | |
| dc.publisher | Universidad Privada de Huancayo Franklin Roosevelt. | |
| dc.publisher.country | PE | |
| dc.rights | https://purl.org/coar/access_right/c_abf2 | |
| dc.rights.uri | http://creativecommons.org/ http://creativecommons.org/licenses/by-nc-nd/4.0//by-nc-nd/4.0/ | |
| dc.source | Repositorio Institucional de la Universidad Privada de Huancayo Franklin Roosevelt | |
| dc.subject | Verbena officinalis L. | |
| dc.subject | Actividad antimicótica | |
| dc.subject | Extracto hidroalcohólico | |
| dc.subject.ocde | http://purl.org/pe-repo/ocde/ford#3.03.00 | |
| dc.title | Evaluación del efecto antimicótico in vitro del extracto hidroalcohólico de hojas de Verbena officinalis L. (verbena) frente a Trichophyton sp. | |
| dc.title.alternative | Evaluation of the in vitro antifungal effect of the hydroalcoholic extract of Verbena officinalis L. (verbena) leaves against Trichophyton sp. | |
| dc.type | http://purl.org/coar/resource_type/c_7a1f | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| renati.advisor.dni | 25748045 | |
| renati.advisor.orcid | https://orcid.org/0000-0002-1103-5319 | |
| renati.author.dni | 43311128 | |
| renati.author.dni | 71482224 | |
| renati.discipline | 917016 | |
| renati.juror | Vicente Manuel, Ayala Picoaga | |
| renati.juror | Mendoza Aire, Jaime Walter | |
| renati.juror | Quezada Reyes, Antonio Fernando | |
| renati.level | http://purl.org/pe-repo/renati/nivel#tituloProfesional | |
| renati.type | http://purl.org/pe-repo/renati/type#tesis | |
| thesis.degree.discipline | Escuela Profesional de Ciencias Farmacéuticas y Bioquímica - Regular | |
| thesis.degree.grantor | Universidad Privada de Huancayo Franklin Roosevelt. Facultad de Ciencias de la Salud | |
| thesis.degree.name | Químico Farmacéutico |
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