Efecto antidiarreico del extracto hidroalcohólico de rizomas de Zingiber officinale (jengibre) en ratones albinos.
| dc.contributor.advisor | Zuñiga Olivera, Consuelo Hibon | es_PE |
| dc.contributor.author | Cieza Chavez, Alex Andres | es_PE |
| dc.contributor.author | Moreno Herhuay, Julio Cesar | es_PE |
| dc.date.accessioned | 2026-03-20T18:40:53Z | |
| dc.date.available | 2026-03-20T18:40:53Z | |
| dc.date.issued | 2026-03-04 | |
| dc.description.abstract | El estudio evaluó el efecto antidiarreico del extracto hidroalcohólico de Zingiber officinale en ratones albinos. Se realizó un estudio experimental con diseño analítico, prospectivo y transversal, utilizando un modelo de tránsito intestinal inducido con carbón activado. 30 ratones BALB/c fueron distribuidos en cinco grupos: control negativo, control positivo con loperamida (1 mg/kg) y tres dosis de extracto (100, 200 y 400 mg/kg) administradas por vía oral. Los resultados mostraron una disminución dosis-dependiente de la motilidad intestinal, siendo la dosis de 400 mg/kg la más efectiva, cercana al efecto de la loperamida, con diferencias significativas (p < 0,05), concluyendo que el extracto tiene un efecto antidiarreico significativo como alternativa natural para tratar la diarrea. | es_PE |
| dc.description.abstract | This study evaluated the antidiarrheal effect of the hydroalcoholic extract of Zingiber officinale in albino mice. An experimental study with an analytical, prospective, and cross-sectional design was conducted using an activated charcoal-induced intestinal transit model. Thirty BALB/c mice were divided into five groups: a negative control, a positive control with loperamide (1 mg/kg), and three doses of the extract (100, 200, and 400 mg/kg) administered orally. The results showed a dose-dependent decrease in intestinal motility, with the 400 mg/kg dose being the most effective, approaching the effect of loperamide, with significant differences (p < 0.05). The study concluded that the extract has a significant antidiarrheal effect as a natural alternative for treating diarrhea. | es_PE |
| dc.format | application/pdf | es_PE |
| dc.identifier.citation | Vancouver | es_PE |
| dc.identifier.uri | https://hdl.handle.net/20.500.14140/2755 | |
| dc.language.iso | spa | es_PE |
| dc.publisher.country | PE | es_PE |
| dc.rights | info:eu-repo/semantics/openAccess | es_PE |
| dc.rights.uri | http://creativecommons.org/licenceses/by-nc-nd/4.0/ | es_PE |
| dc.source | Universidad Privada de Huancayo Franklin Roosevelt | es_PE |
| dc.subject | Zingiber officinale, efecto antidiarreico, extracto hidroalcohólico | es_PE |
| dc.subject.ocde | http://purl.org/pe-repo/ocde/ford#3.01.05 | es_PE |
| dc.title | Efecto antidiarreico del extracto hidroalcohólico de rizomas de Zingiber officinale (jengibre) en ratones albinos. | es_PE |
| dc.title.alternative | Antidiarrheal effect of the hydroalcoholic extract of Zingiber officinale (ginger) rhizomes in albino mice. | es_PE |
| dc.type | info:eu-repo/semantics/bachelorThesis | es_PE |
| dc.type.version | info:eu-repo/semantics/publishedVersion | es_PE |
| renati.advisor.dni | 40754430 | |
| renati.advisor.orcid | https://orcid.org/0000-0001-7375-9913 | es_PE |
| renati.author.dni | 73204434 | |
| renati.author.dni | 46501435 | |
| renati.discipline | 917016 | es_PE |
| renati.juror | Solgorre Contreras, Enrique Juan | es_PE |
| renati.juror | Churango Valdez, Javier Florentino | es_PE |
| renati.juror | Obando Barrera, Lucio Henry | es_PE |
| renati.level | http://purl.org/pe-repo/renati/nivel#tituloProfesional | es_PE |
| renati.type | http://purl.org/pe-repo/renati/type#tesis | es_PE |
| thesis.degree.discipline | Escuela profesional de Ciencias Farmacéuticas y Bioquímica | es_PE |
| thesis.degree.grantor | Universidad Privada de Huancayo Franklin Roosevelt. Escuela Profesional De Ciencias Farmacéuticas y Bioquímica - Regular | es_PE |
| thesis.degree.name | Químico Farmacéutico | es_PE |
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